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Cofactor molecules: Essential partners for infectious prions
The protein-only hypothesis predicts that infectious mammalian prions are composed solely of PrP(Sc), a misfolded conformer of the normal prion protein, PrP(C). However, to date, all wild type protein-only PrP(Sc) preparations lack significant levels of prion infectivity. Using a systemic biochemica...
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| Publicado no: | Prog Mol Biol Transl Sci |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7768309/ https://ncbi.nlm.nih.gov/pubmed/32958241 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.pmbts.2020.07.009 |
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