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Dissociation of recombinant prion autocatalysis from infectivity
Within the mammalian prion field, the existence of recombinant prion protein (PrP) conformers with self-replicating (ie. autocatalytic) activity in vitro but little to no infectious activity in vivo challenges a key prediction of the protein-only hypothesis of prion replication – that autocatalytic...
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| Vydáno v: | Prion |
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| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Taylor & Francis
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4964854/ https://ncbi.nlm.nih.gov/pubmed/26645356 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336896.2015.1123843 |
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