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Photodegradation illuminates the role of polyanions in prion infectivity

Understanding the mechanism by which prion infectivity is encoded by the misfolded protein PrP(Sc) remains a high priority within the prion field. Work from several groups has indicated cellular cofactors may be necessary to form infectious prions in vitro. The identity of endogenous prion conversio...

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Bibliographic Details
Main Authors: Piro, Justin R, Supattapone, Surachai
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166499/
https://ncbi.nlm.nih.gov/pubmed/21646861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.5.2.16155
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