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Complex Polyamines: Unique Prion Disaggregating Compounds

Among the candidate anti-prion chemotherapeutic agents identified to date, complex polyamines constitute the only class of compounds that possess the ability to remove pre-existing PrP(Sc) molecules from infected cells. The potency of branched polyamines such as cationic dendrimers increases with th...

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Main Authors: Supattapone, Surachai, Piro, Justin R., Rees, Judy R.
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019611/
https://ncbi.nlm.nih.gov/pubmed/19702574
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