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The effects of prion protein proteolysis and disaggregation on the strain properties of hamster scrapie
Native mammalian prions exist in self-propagating strains that exhibit distinctive clinical, pathological and biochemical characteristics. Prion strain diversity is associated with variations in PrP(Sc) conformation, but it remains unknown precisely which physical properties of the PrP(Sc) molecules...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2675185/ https://ncbi.nlm.nih.gov/pubmed/18796735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.2008/002303-0 |
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