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Amplification of Purified Prions In Vitro
The infectious agents of prion diseases are unorthodox, and appear to be composed primarily of a misfolded glycoprotein called the prion protein (PrP). Replication of prion infectivity is associated with the conversion of PrP from its normal, cellular form (PrP(C)) into a pathogenic form (PrP(Sc)),...
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Auteurs principaux: | , , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
2008
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2700657/ https://ncbi.nlm.nih.gov/pubmed/18576152 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-59745-234-2_9 |
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