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Amplification of Purified Prions In Vitro

The infectious agents of prion diseases are unorthodox, and appear to be composed primarily of a misfolded glycoprotein called the prion protein (PrP). Replication of prion infectivity is associated with the conversion of PrP from its normal, cellular form (PrP(C)) into a pathogenic form (PrP(Sc)),...

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Detalhes bibliográficos
Main Authors: Supattapone, Surachai, Deleault, Nathan R., Rees, Judy R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2700657/
https://ncbi.nlm.nih.gov/pubmed/18576152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-59745-234-2_9
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