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Superparamagnetic Nanoparticle Capture of Prions for Amplification
Prion diseases are associated with the presence of PrP(Sc), a disease-associated misfolded conformer of the prion protein. We report that superparamagnetic nanoparticles bind PrP(Sc) molecules efficiently and specifically, permitting magnetic separation of prions from a sample mixture. Captured PrP(...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3067916/ https://ncbi.nlm.nih.gov/pubmed/21228242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02451-10 |
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