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Superparamagnetic Nanoparticle Capture of Prions for Amplification

Prion diseases are associated with the presence of PrP(Sc), a disease-associated misfolded conformer of the prion protein. We report that superparamagnetic nanoparticles bind PrP(Sc) molecules efficiently and specifically, permitting magnetic separation of prions from a sample mixture. Captured PrP(...

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Detalles Bibliográficos
Autores principales: Miller, Michael B., Supattapone, Surachai
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067916/
https://ncbi.nlm.nih.gov/pubmed/21228242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02451-10
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