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In Situ Photodegradation of Incorporated Polyanion Does Not Alter Prion Infectivity
Single-stranded polyanions ≥40 bases in length facilitate the formation of hamster scrapie prions in vitro, and polyanions co-localize with PrP(Sc) aggregates in vivo [1], [2]. To test the hypothesis that intact polyanionic molecules might serve as a structural backbone essential for maintaining the...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3033378/ https://ncbi.nlm.nih.gov/pubmed/21304885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002001 |
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