טוען...
Conformational changes in IgE contribute to its uniquely slow dissociation rate from receptor FcεRI
Of all the antibody classes, IgE displays a uniquely slow dissociation rate from, and high affinity for, its cell surface receptor FcεRI. The structural basis for these key determinants of IgE’s ability to mediate allergic hypersensitivity is now revealed by the 3.4Å resolution crystal structure of...
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| Main Authors: | , , , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2011
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3357048/ https://ncbi.nlm.nih.gov/pubmed/21516097 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2044 |
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