Loss of c-Met Accelerates Development of Liver Fibrosis in Response to CCl(4) Exposure through Deregulation of Multiple Molecular Pathways

HGF/c-Met signaling plays a pivotal role in hepatocyte survival and tissue remodeling during liver regeneration. HGF treatment accelerates resolution of fibrosis in experimental animal models. Here, we utilized Met(fl/fl);Alb-Cre(+/−) conditional knockout mice and a carbon tetrachloride(CCl(4))-indu...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Marquardt, Jens U, Seo, Daekwan, Gomez-Quiroz, Luis E, Uchida, Koichi, Gillen, Matthew C, Kitade, Mitsuteru, Kaposi-Novak, Pal, Conner, Elizabeth A, Factor, Valentina M, Thorgeirsson, Snorri S
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3338880/
https://ncbi.nlm.nih.gov/pubmed/22386877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2012.02.012
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados