A DNA hypermethylation module for the stem/progenitor cell signature of cancer

Many DNA-hypermethylated cancer genes are occupied by the Polycomb (PcG) repressor complex in embryonic stem cells (ESCs). Their prevalence in the full spectrum of cancers, the exact context of chromatin involved, and their status in adult cell renewal systems are unknown. Using a genome-wide analys...

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書誌詳細
主要な著者: Easwaran, Hariharan, Johnstone, Sarah E., Van Neste, Leander, Ohm, Joyce, Mosbruger, Tim, Wang, Qiuju, Aryee, Martin J., Joyce, Patrick, Ahuja, Nita, Weisenberger, Dan, Collisson, Eric, Zhu, Jingchun, Yegnasubramanian, Srinivasan, Matsui, William, Baylin, Stephen B.
フォーマット: Artigo
言語:Inglês
出版事項: Cold Spring Harbor Laboratory Press 2012
主題:
Research
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3337430/
https://ncbi.nlm.nih.gov/pubmed/22391556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.131169.111
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