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Defining a Chromatin Pattern That Characterizes DNA Hypermethylated Genes in Colon Cancer Cells

Epigenetic gene regulation is a key determinant of heritable gene expression patterns and is critical for normal cellular function. Dysregulation of epigenetic transcriptional control is a fundamental feature of cancer, particularly manifesting as increased promoter DNA methylation with associated a...

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Detalles Bibliográficos
Main Authors: McGarvey, Kelly M., Van Neste, Leander, Cope, Leslie, Ohm, Joyce E., Herman, James G., Van Criekinge, Wim, Schuebel, Kornel E., Baylin, Stephen B.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2706536/
https://ncbi.nlm.nih.gov/pubmed/18632628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-0700
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