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Increased mitochondrial biogenesis in muscle improves aging phenotypes in the mtDNA mutator mouse
Aging is an intricate process that increases susceptibility to sarcopenia and cardiovascular diseases. The accumulation of mitochondrial DNA (mtDNA) mutations is believed to contribute to mitochondrial dysfunction, potentially shortening lifespan. The mtDNA mutator mouse, a mouse model with a proofr...
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| Hlavní autoři: | , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3335313/ https://ncbi.nlm.nih.gov/pubmed/22357654 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds049 |
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