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Transient systemic mtDNA damage leads to muscle wasting by reducing the satellite cell pool

With age, muscle mass and integrity are progressively lost leaving the elderly frail, weak and unable to independently care for themselves. Defined as sarcopenia, this age-related muscle atrophy appears to be multifactorial but its definite cause is still unknown. Mitochondrial dysfunction has been...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Wang, Xiao, Pickrell, Alicia M., Rossi, Susana G., Pinto, Milena, Dillon, Lloye M., Hida, Aline, Rotundo, Richard L., Moraes, Carlos T.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3766186/
https://ncbi.nlm.nih.gov/pubmed/23760083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt251
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