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Transient systemic mtDNA damage leads to muscle wasting by reducing the satellite cell pool

With age, muscle mass and integrity are progressively lost leaving the elderly frail, weak and unable to independently care for themselves. Defined as sarcopenia, this age-related muscle atrophy appears to be multifactorial but its definite cause is still unknown. Mitochondrial dysfunction has been...

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Autors principals: Wang, Xiao, Pickrell, Alicia M., Rossi, Susana G., Pinto, Milena, Dillon, Lloye M., Hida, Aline, Rotundo, Richard L., Moraes, Carlos T.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3766186/
https://ncbi.nlm.nih.gov/pubmed/23760083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt251
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