Therapeutic targeting of cancers with loss of PTEN function

by Dillon, Lloye M., Miller, Todd W.
Published in Curr Drug Targets (2014)

The PREX1/Rac signaling axis: Potential as a biomarker and therapeutic target in breast cancer

by Dillon, Lloye M, Miller, Todd W
Published in Mol Cell Oncol (2015)

The Role of PGC-1 Coactivators in Aging Skeletal Muscle and Heart

by Dillon, Lloye M., Rebelo, Adriana P., Moraes, Carlos T.
Published 2012

Long-Term Bezafibrate Treatment Improves Skin and Spleen Phenotypes of the mtDNA Mutator Mouse

by Dillon, Lloye M., Hida, Aline, Garcia, Sofia, Prolla, Tomas A., Moraes, Carlos T.
Published 2012

Increased mitochondrial biogenesis in muscle improves aging phenotypes in the mtDNA mutator mouse

by Dillon, Lloye M., Williams, Siôn L., Hida, Aline, Peacock, Jacqueline D., Prolla, Tomas A., Lincoln, Joy, Moraes, Carlos T.
Published 2012

Transient systemic mtDNA damage leads to muscle wasting by reducing the satellite cell pool

by Wang, Xiao, Pickrell, Alicia M., Rossi, Susana G., Pinto, Milena, Dillon, Lloye M., Hida, Aline, Rotundo, Richard L., Moraes, Carlos T.
Published 2013

Estrogen receptor alpha and androgen receptor are commonly expressed in well-differentiated liposarcoma

by Ingram, Davis R, Dillon, Lloye M, Lev, Dina Chelouche, Lazar, Alexander, Demicco, Elizabeth G, Eisenberg, Burton L, Miller, Todd W
Published 2014

A tumor specific antibody to aid breast cancer screening in women with dense breast tissue

by Roy, Lopamudra Das, Dillon, Lloye M., Zhou, Ru, Moore, Laura J., Livasy, Chad, El-Khoury, Joe M., Puri, Rahul, Mukherjee, Pinku
Published in Genes Cancer (2017)

Combined inhibition of both p110α and p110β isoforms of phosphatidylinositol 3-kinase is required for sustained therapeutic effect in PTEN-deficient, ER+ breast cancer

by Hosford, Sarah R., Dillon, Lloye M., Bouley, Stephanie J., Rosati, Rachele, Yang, Wei, Chen, Vivian S., Demidenko, Eugene, Morra, Rocco P., Miller, Todd W.
Published in Clin Cancer Res (2016)

The mtDNA mutation spectrum of the progeroid Polg mutator mouse includes abundant control region multimers

by Williams, Siôn L., Huang, Jia, Edwards, Yvonne J.K., Ulloa, Rick H., Dillon, Lloye M., Prolla, Tomas A., Vance, Jeffery M., Moraes, Carlos T., Züchner, Stephan
Published 2010

Transient mitochondrial DNA double strand breaks in mice cause accelerated aging phenotypes in a ROS-dependent but p53/p21-independent manner

by Pinto, Milena, Pickrell, Alicia M, Wang, Xiao, Bacman, Sandra R, Yu, Aixin, Hida, Aline, Dillon, Lloye M, Morton, Paul D, Malek, Thomas R, Williams, Siôn L, Moraes, Carlos T
Published in Cell Death Differ (2017)

Antibody-Guided In Vivo Imaging for Early Detection of Mammary Gland Tumors()()

by Moore, Laura Jeffords, Roy, Lopamudra Das, Zhou, Ru, Grover, Priyanka, Wu, Shu-ta, Curry, Jennifer M., Dillon, Lloye M., Puri, Priya M., Yazdanifar, Mahboubeh, Puri, Rahul, Mukherjee, Pinku, Dréau, Didier
Published in Transl Oncol (2016)

P-REX1 creates a positive feedback loop to activate growth factor receptor, PI3K/AKT, and MEK/ERK signaling in breast cancer

by Dillon, Lloye M., Bean, Jennifer R., Yang, Wei, Shee, Kevin, Symonds, Lynn K., Balko, Justin M., McDonald, W. Hayes, Liu, Shuying, Gonzalez-Angulo, Ana M., Mills, Gordon B., Arteaga, Carlos L., Miller, Todd W.
Published in Oncogene (2014)

The PI3K/mTOR dual inhibitor P7170 demonstrates potent activity against endocrine-sensitive and endocrine-resistant ER+ breast cancer

by Bean, Jennifer R., Hosford, Sarah R., Symonds, Lynn K., Owens, Philip, Dillon, Lloye M., Yang, Wei, Shee, Kevin, Schwartz, Gary N., Marotti, Jonathan D., Muller, Kristen E., Rosenkranz, Kari M., Barth, Richard J., Chen, Vivian S., Agarwal, Veena R., Miller, Todd W.
Published in Breast Cancer Res Treat (2014)

Strategically timing inhibition of phosphatidylinositol 3-kinase to maximize therapeutic index in estrogen receptor alpha-positive, PIK3CA-mutant breast cancer

by Yang, Wei, Hosford, Sarah R., Dillon, Lloye M., Shee, Kevin, Liu, Stephanie C., Bean, Jennifer R., Salphati, Laurent, Pang, Jodie, Zhang, Xiaolin, Nannini, Michelle A., Demidenko, Eugene, Bates, Darcy, Lewis, Lionel D., Marotti, Jonathan D., Eastman, Alan R., Miller, Todd W.
Published in Clin Cancer Res (2016)

AMPK activation by metformin promotes survival of dormant ER+ breast cancer cells

by Hampsch, Riley A., Wells, Jason D., Traphagen, Nicole A., McCleery, Charlotte F., Fields, Jennifer L., Shee, Kevin, Dillon, Lloye M., Pooler, Darcy B., Lewis, Lionel D., Demidenko, Eugene, Huang, Yina H., Marotti, Jonathan D., Goen, Abigail E., Kinlaw, William B., Miller, Todd W.
Published in Clin Cancer Res (2020)