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In vivo methylation of mtDNA reveals the dynamics of protein–mtDNA interactions

To characterize the organization of mtDNA–protein complexes (known as nucleoids) in vivo, we have probed the mtDNA surface exposure using site-specific DNA methyltransferases targeted to the mitochondria. We have observed that DNA methyltransferases have different accessibility to different sites on...

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Bibliographic Details
Main Authors: Rebelo, Adriana P., Williams, Sion L., Moraes, Carlos T.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777446/
https://ncbi.nlm.nih.gov/pubmed/19740762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp727
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