טוען...
Somatic mtDNA Mutation Spectra in the Aging Human Putamen
The accumulation of heteroplasmic mitochondrial DNA (mtDNA) deletions and single nucleotide variants (SNVs) is a well-accepted facet of the biology of aging, yet comprehensive mutation spectra have not been described. To address this, we have used next generation sequencing of mtDNA-enriched librari...
שמור ב:
| Main Authors: | , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Public Library of Science
2013
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3854840/ https://ncbi.nlm.nih.gov/pubmed/24339796 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003990 |
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