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Somatic mtDNA Mutation Spectra in the Aging Human Putamen
The accumulation of heteroplasmic mitochondrial DNA (mtDNA) deletions and single nucleotide variants (SNVs) is a well-accepted facet of the biology of aging, yet comprehensive mutation spectra have not been described. To address this, we have used next generation sequencing of mtDNA-enriched librari...
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| Hoofdauteurs: | , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Public Library of Science
2013
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3854840/ https://ncbi.nlm.nih.gov/pubmed/24339796 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003990 |
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