Germline and somatic mtDNA mutations in mouse aging

The accumulation of acquired mitochondrial genome (mtDNA) mutations with aging in somatic cells has been implicated in mitochondrial dysfunction and linked to age-onset diseases in humans. Here, we asked if somatic mtDNA mutations are also associated with aging in the mouse. MtDNA integrity in multi...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:PLoS One
मुख्य लेखकों: Ma, Hong, Lee, Yeonmi, Hayama, Tomonari, Van Dyken, Crystal, Marti-Gutierrez, Nuria, Li, Ying, Ahmed, Riffat, Koski, Amy, Kang, Eunju, Darby, Hayley, Gonmanee, Thanasup, Park, Younjung, Wolf, Don P., Jai Kim, Chong, Mitalipov, Shoukhrat
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2018
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6057648/
https://ncbi.nlm.nih.gov/pubmed/30040856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0201304
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