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Evidence for a mammalian late-G(1) phase inhibitor of replication licensing distinct from geminin or Cdk activity

Pre-replication complexes (pre-RCs) are assembled onto DNA during late mitosis and G(1) to license replication origins for use in S phase. In order to prevent re-replication of DNA, licensing must be completely shutdown prior to entry into S phase. While mechanisms preventing re-replication during S...

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Bibliografische gegevens
Hoofdauteurs: Sasaki, Takayo, Li, Anatoliy, Gillespie, Peter J, Blow, J Julian, Gilbert, David M
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Landes Bioscience 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322585/
https://ncbi.nlm.nih.gov/pubmed/21983086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/nucl.2.5.17859
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