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Evidence for a mammalian late-G(1) phase inhibitor of replication licensing distinct from geminin or Cdk activity
Pre-replication complexes (pre-RCs) are assembled onto DNA during late mitosis and G(1) to license replication origins for use in S phase. In order to prevent re-replication of DNA, licensing must be completely shutdown prior to entry into S phase. While mechanisms preventing re-replication during S...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Landes Bioscience
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3322585/ https://ncbi.nlm.nih.gov/pubmed/21983086 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/nucl.2.5.17859 |
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