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Mammalian nuclei become licensed for DNA replication during late telophase

Mcm 2–7 are essential replication proteins that bind to chromatin in mammalian nuclei during late telophase. Here, we have investigated the relationship between Mcm binding, licensing of chromatin for replication, and specification of the dihydrofolate reductase (DHFR) replication origin. Approximat...

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Autors principals: Dimitrova, Daniela S., Prokhorova, Tatyana A., Blow, J. Julian, Todorov, Ivan T., Gilbert, David M.
Format: Artigo
Idioma:Inglês
Publicat: 2002
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1255924/
https://ncbi.nlm.nih.gov/pubmed/11801723
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