Reconstitution of licensed replication origins on Xenopus sperm nuclei using purified proteins

BACKGROUND: In order to ensure precise chromosome duplication, eukaryotes "license" their replication origins during late mitosis and early G1 by assembling complexes of Mcm2-7 onto them. Mcm2-7 are essential for DNA replication, but are displaced from origins as they initiate, thus ensuring that no...

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Detalhes bibliográficos

Publicado no:	BMC Biochem
Principais autores:	Gillespie, Peter J, Li, Anatoliy, Blow, J Julian
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2001
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC60996/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11737877/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1471-2091-2-15
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