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Reconstitution of licensed replication origins on Xenopus sperm nuclei using purified proteins

BACKGROUND: In order to ensure precise chromosome duplication, eukaryotes "license" their replication origins during late mitosis and early G1 by assembling complexes of Mcm2-7 onto them. Mcm2-7 are essential for DNA replication, but are displaced from origins as they initiate, thus ensuri...

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Detalhes bibliográficos
Main Authors: Gillespie, Peter J, Li, Anatoliy, Blow, J Julian
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC60996/
https://ncbi.nlm.nih.gov/pubmed/11737877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-2-15
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