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Xenopus Cdc7 function is dependent on licensing but not on XORC, XCdc6, or CDK activity and is required for XCdc45 loading

The assembly and disassembly of protein complexes at replication origins play a crucial role in the regulation of chromosomal DNA replication. The sequential binding of the origin recognition complex (ORC), Cdc6, and the minichromosome maintenance (MCM/P1) proteins produces a licensed replication or...

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Bibliographic Details
Main Authors: Jares, Pedro, Blow, J. Julian
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2000
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC316685/
https://ncbi.nlm.nih.gov/pubmed/10859170
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