Reconstitution of licensed replication origins on Xenopus sperm nuclei using purified proteins
BACKGROUND: In order to ensure precise chromosome duplication, eukaryotes "license" their replication origins during late mitosis and early G1 by assembling complexes of Mcm2-7 onto them. Mcm2-7 are essential for DNA replication, but are displaced from origins as they initiate, thus ensuring that no...
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| Udgivet i: | BMC Biochem |
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| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BMC
2001
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC60996/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11737877/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1471-2091-2-15 |
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