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Sequential MCM/P1 subcomplex assembly is required to form a hetero-hexamer with replication licensing activity

Replication Licensing Factor (RLF) is a multiprotein complex involved in ensuring that chromosomal DNA replicates only once in a single cell cycle. It comprises two components, termed RLF-M and RLF-B. Purified RLF-M consists of a mixture of complexes containing all 6 members of the MCM/P1 family of...

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Detalhes bibliográficos
Main Authors: Prokhorova, Tatyana A., Blow, J. Julian
Formato: Artigo
Idioma:Inglês
Publicado em: 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3626232/
https://ncbi.nlm.nih.gov/pubmed/10644704
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