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MCM2-7 Form Double Hexamers at Licensed Origins in Xenopus Egg Extract
In late mitosis and G1, Mcm2-7 are assembled onto replication origins to license them for initiation in the upcoming S phase. After initiation, Mcm2-7 provide helicase activity to unwind DNA at the replication fork. Here we examine the structure of Mcm2-7 on chromatin in Xenopus egg extracts. We sho...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3064236/ https://ncbi.nlm.nih.gov/pubmed/21282109 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.199521 |
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