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Xenopus Mcm10 is a CDK-substrate required for replication fork stability

During S phase, following activation of the S phase CDKs and the DBF4-dependent kinases (DDK), double hexamers of Mcm2-7 at licensed replication origins are activated to form the core replicative helicase. Mcm10 is one of several proteins that have been implicated from work in yeasts to play a role...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cell Cycle
Hauptverfasser: Chadha, Gaganmeet Singh, Gambus, Agnieszka, Gillespie, Peter J., Blow, J. Julian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4993430/
https://ncbi.nlm.nih.gov/pubmed/27327991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1199305
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