A carregar...
Reversal of DDK-Mediated MCM Phosphorylation by Rif1-PP1 Regulates Replication Initiation and Replisome Stability Independently of ATR/Chk1
Dbf4-dependent kinases (DDKs) are required for the initiation of DNA replication, their essential targets being the MCM2-7 proteins. We show that, in Xenopus laevis egg extracts and human cells, hyper-phosphorylation of DNA-bound Mcm4, but not phosphorylation of Mcm2, correlates with DNA replication...
Na minha lista:
| Publicado no: | Cell Rep |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cell Press
2017
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5357733/ https://ncbi.nlm.nih.gov/pubmed/28273463 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.02.042 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|