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An Essential Role for MCL-1 in ATR-mediated CHK1 Phosphorylation

Here we report a novel role for myeloid cell leukemia 1 (Mcl-1), a Bcl-2 family member, in regulating phosphorylation and activation of DNA damage checkpoint kinase, Chk1. Increased expression of nuclear Mcl-1 and/or a previously reported short nuclear form of Mcl-1, snMcl-1, was observed in respons...

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Main Authors: Jamil, Sarwat, Mojtabavi, Shadi, Hojabrpour, Payman, Cheah, Stefanie, Duronio, Vincent
格式: Artigo
語言:Inglês
出版: The American Society for Cell Biology 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2488305/
https://ncbi.nlm.nih.gov/pubmed/18495871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-11-1171
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