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ATR-Mediated Checkpoint Pathways Regulate Phosphorylation and Activation of Human Chk1

Chk1 is an evolutionarily conserved protein kinase that regulates cell cycle progression in response to checkpoint activation. In this study, we demonstrated that agents that block DNA replication or cause certain forms of DNA damage induce the phosphorylation of human Chk1. The phosphorylated form...

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Detaylı Bibliyografya
Asıl Yazarlar: Zhao, Hui, Piwnica-Worms, Helen
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2001
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC87074/
https://ncbi.nlm.nih.gov/pubmed/11390642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.13.4129-4139.2001
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