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ATR-Mediated Checkpoint Pathways Regulate Phosphorylation and Activation of Human Chk1
Chk1 is an evolutionarily conserved protein kinase that regulates cell cycle progression in response to checkpoint activation. In this study, we demonstrated that agents that block DNA replication or cause certain forms of DNA damage induce the phosphorylation of human Chk1. The phosphorylated form...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology
2001
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC87074/ https://ncbi.nlm.nih.gov/pubmed/11390642 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.13.4129-4139.2001 |
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