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ATR-Mediated Checkpoint Pathways Regulate Phosphorylation and Activation of Human Chk1

Chk1 is an evolutionarily conserved protein kinase that regulates cell cycle progression in response to checkpoint activation. In this study, we demonstrated that agents that block DNA replication or cause certain forms of DNA damage induce the phosphorylation of human Chk1. The phosphorylated form...

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Dades bibliogràfiques
Publicat a:Mol Cell Biol
Autors principals: Zhao, Hui, Piwnica-Worms, Helen
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2001
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC87074/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11390642/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.13.4129-4139.2001
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