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A proteolytic fragment of Mcl-1 exhibits nuclear localization and regulates cell growth by interaction with Cdk1

Mcl-1 (myeloid cell leukaemia-1) is a Bcl-2 family member with short-term pro-survival functions but whose other functions, demonstrated by embryonic lethality of knockout mice, do not involve apoptosis. In the present study, we show a cell-cycle-regulatory role of Mcl-1 involving a shortened form o...

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Autors principals: Jamil, Sarwat, Sobouti, Rafat, Hojabrpour, Payman, Raj, Meera, Kast, Juergen, Duronio, Vincent
Format: Artigo
Idioma:Inglês
Publicat: Portland Press Ltd. 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1134995/
https://ncbi.nlm.nih.gov/pubmed/15554878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20041596
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