Structural, energetic and dynamic properties of guanine(C8)–thymine(N3) cross-links in DNA provide insights on susceptibility to nucleotide excision repair

The one-electron oxidation of guanine in DNA by carbonate radical anions, a decomposition product of peroxynitrosocarbonate which is associated with the inflammatory response, can lead to the formation of intrastrand cross-links between guanine and thymine bases [Crean et al. (Oxidation of single-st...

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Detalhes bibliográficos
Main Authors: Ding, Shuang, Kropachev, Konstantin, Cai, Yuqin, Kolbanovskiy, Marina, Durandina, Svetlana A., Liu, Zhi, Shafirovich, Vladimir, Broyde, Suse, Geacintov, Nicholas E.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Genome Integrity, Repair and Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315297/
https://ncbi.nlm.nih.gov/pubmed/22135299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr1087
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