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Methoxychalcone Inhibitors of Androgen Receptor Translocation and Function

Androgen receptor activity drives incurable castrate-resistant prostate cancer. All approved antiandrogens inhibit androgen receptor-driven transcription, and in addition the second-generation antiandrogen MDV3100 inhibits ligand-activated androgen receptor nuclear translocation, via an unknown mech...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kim, Yeong Sang, Kumar, Vineet, Lee, Sunmin, Iwai, Aki, Neckers, Len, Malhotra, Sanjay V., Trepel, Jane B.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308679/
https://ncbi.nlm.nih.gov/pubmed/22310230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2011.12.141
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