An Electrophoretic Mobility Shift Assay Identifies a Mechanistically Unique Inhibitor of Protein Sumoylation

Autor Kim, Yeong Sang, Nagy, Katelyn, Keyser, Samantha, Schneekloth, John S.
Vydáno 2013

Synthesis of 2’,3’,4’-trihydroxyflavone (2-D08), an Inhibitor of Protein Sumoylation

Autor Kim, Yeong Sang, Keyser, Samantha G. L., Schneekloth, John S.
Vydáno 2014

Casein kinase 2 phosphorylation of Hsp90 threonine 22 modulates chaperone function and drug sensitivity

Autor Mollapour, Mehdi, Tsutsumi, Shinji, Kim, Yeong Sang, Trepel, Jane, Neckers, Len
Vydáno 2011

Synthetic derivatives of the SUMO consensus sequence provide a basis for improved substrate recognition

Autor Leyva, Melissa J., Kim, Yeong Sang, Peach, Megan L., Schneekloth, John S.
Vydáno v Bioorg Med Chem Lett (2015)

Histone deacetylase inhibitors in cancer therapy

Autor Lee, Min-Jung, Kim, Yeong Sang, Kummar, Shivaani, Giaccone, Giuseppe, Trepel, Jane B.
Vydáno v Curr Opin Oncol (2008)

Methoxychalcone Inhibitors of Androgen Receptor Translocation and Function

Autor Kim, Yeong Sang, Kumar, Vineet, Lee, Sunmin, Iwai, Aki, Neckers, Len, Malhotra, Sanjay V., Trepel, Jane B.
Vydáno 2012

Pharmacodynamic Assessment of Histone Deacetylase Inhibitors: Infrared Vibrational Spectroscopic Imaging of Protein Acetylation

Autor Chen, Tsoching, Lee, Min-Jung, Kim, Yeong Sang, Lee, Sunmin, Kummar, Shivaani, Gutierrez, Martin, Hewitt, Stephen M, Trepel, Jane B., Levin, Ira W
Vydáno 2008

Synthesis and structure–activity relationship studies of novel dihydropyridones as androgen receptor modulators

Autor Pepe, Antonella, Pamment, Michael, Kim, Yeong Sang, Lee, Sunmin, Lee, Min-Jung, Beebe, Kristin, Filikov, Anton, Neckers, Len, Trepel, Jane, Malhotra, Sanjay V.
Vydáno v J Med Chem (2013)

Inhibition of Tumor Cell Motility by the Interferon-inducible GTPase MxA

Autor Mushinski, J. Frederic, Nguyen, PhuongMai, Stevens, Lisa M., Khanna, Chand, Lee, Sunmin, Chung, Eun Joo, Lee, Min-Jung, Kim, Yeong Sang, Linehan, W. Marston, Horisberger, Michel A., Trepel, Jane B.
Vydáno 2009

A gene-expression screen identifies a non-toxic sumoylation inhibitor that mimics SUMO-less human LRH-1 in liver

Autor Suzawa, Miyuki, Miranda, Diego A, Ramos, Karmela A, Ang, Kenny K-H, Faivre, Emily J, Wilson, Christopher G, Caboni, Laura, Arkin, Michelle R, Kim, Yeong-Sang, Fletterick, Robert J, Diaz, Aaron, Schneekloth, John S, Ingraham, Holly A
Vydáno v eLife (2015)

1,4-Substituted Triazoles as Nonsteroidal Anti-Androgens for Prostate Cancer Treatment

Autor Ferroni, Claudia, Pepe, Antonella, Kim, Yeong Sang, Lee, Sunmin, Guerrini, Andrea, Parenti, Marco Daniele, Tesei, Anna, Zamagni, Alice, Cortesi, Michela, Zaffaroni, Nadia, De Cesare, Michelandrea, Beretta, Giovanni Luca, Trepel, Jane B., Malhotra, Sanjay V., Varchi, Greta
Vydáno v J Med Chem (2017)

A Phase 1 study of PF-04929113 (SNX-5422), an orally bioavailable heat shock protein 90 inhibitor in patients with refractory solid tumor malignancies and lymphomas

Autor Rajan, Arun, Kelly, Ronan J., Trepel, Jane B., Kim, Yeong Sang, Alarcon, Sylvia V., Kummar, Shivaani, Gutierrez, Martin, Crandon, Sonja, Zein, Wadih M., Jain, Lokesh, Mannargudi, Baskar, Figg, William D., Houk, Brett E., Shnaidman, Michael, Brega, Nicoletta, Giaccone, Giuseppe
Vydáno 2011

Phase I Trial of Vandetanib and Bevacizumab Evaluating the VEGF and EGF Signal Transduction Pathways in Adults With Solid Tumours and Lymphomas

Autor Kummar, Shivaani, Gutierrez, Martin E., Chen, Alice, Turkbey, Ismail B., Allen, Deborah, Horneffer, Yvonne R., Juwara, Lamin, Cao, Liang, Yu, Yunkai, Kim, Yeong Sang, Trepel, Jane, Chen, Helen, Choyke, Peter, Melillo, Giovanni, Murgo, Anthony J., Collins, Jerry, Doroshow, James H.
Vydáno 2011

The glycolytic shift in fumarate-hydratase-deficient kidney cancer lowers AMPK levels, increases anabolic propensities and lowers cellular iron levels

Autor Tong, Wing-Hang, Sourbier, Carole, Kovtunovych, Gennady, Jeong, Suh Young, Vira, Manish, Ghosh, Manik, Romero, Vladimir Valera, Sougrat, Rachid, Vaulont, Sophie, Viollet, Benoit, Kim, Yeong-Sang, Lee, Sunmin, Trepel, Jane, Srinivasan, Ramaprasad, Bratslavsky, Gennady, Yang, Youfeng, Linehan, W. Marston, Rouault, Tracey A.
Vydáno 2011

Phase II Trial of Bevacizumab, Thalidomide, Docetaxel, and Prednisone in Patients With Metastatic Castration-Resistant Prostate Cancer

Autor Ning, Yang-Min, Gulley, James L., Arlen, Philip M., Woo, Sukyung, Steinberg, Seth M., Wright, John J., Parnes, Howard L., Trepel, Jane B., Lee, Min-Jung, Kim, Yeong Sang, Sun, Haihao, Madan, Ravi A., Latham, Lea, Jones, Elizabeth, Chen, Clara C., Figg, William D., Dahut, William L.
Vydáno 2010

Targeting the Hsp40/Hsp70 chaperone axis as a novel strategy to treat castration-resistant prostate cancer

Autor Moses, Michael A., Kim, Yeong Sang, Rivera-Marquez, Genesis M., Oshima, Nobu, Watson, Matthew J., Beebe, Kristin E., Wells, Catherine, Lee, Sunmin, Zuehlke, Abbey D., Shao, Hao, Bingman, William E., Kumar, Vineet, Malhotra, Sanjay V., Weigel, Nancy L., Gestwicki, Jason E., Trepel, Jane B., Neckers, Leonard M.
Vydáno v Cancer Res (2018)