Hypoxia-inducible factor induction by tumour necrosis factor in normoxic cells requires receptor-interacting protein-dependent nuclear factor kappa B activation.

Tumour necrosis factor alpha (TNF-alpha) binds to its receptor (TNFR1) and activates both death- and inflammation/survival-related signalling pathways. The inflammation and survival-related signalling cascade results in the activation of the transcription factor, nuclear factor kappa B (NF-kappa B)...

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Detalhes bibliográficos
Main Authors: Jung, YunJin, Isaacs, Jennifer S, Lee, Sunmin, Trepel, Jane, Liu, Zheng-Gang, Neckers, Len
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223232/
https://ncbi.nlm.nih.gov/pubmed/12479793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20021279
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