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Tumour necrosis factor receptor 1 mediates endoplasmic reticulum stress-induced activation of the MAP kinase JNK

Tumour necrosis factor receptor (TNFR)1 is the main receptor responsible for TNF-induced diverse cellular events. In this study, we report that TNFR1 has a crucial role in endoplasmic reticulum (ER) stress-induced Jun amino-terminal kinase (JNK) activation. Although ER stress leads to JNK activation...

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Detalhes bibliográficos
Main Authors: Yang, Qingfeng, Kim, You-Sun, Lin, Yong, Lewis, Joseph, Neckers, Len, Liu, Zheng-Gang
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1479600/
https://ncbi.nlm.nih.gov/pubmed/16680093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400687
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