טוען...
G protein-coupled receptor inactivation by an allosteric inverse-agonist antibody
G protein-coupled receptors (GPCRs) are the largest class of cell-surface receptors, and these membrane proteins exist in equilibrium between inactive and active states.(1-13) Conformational changes induced by extracellular ligands binding to GPCRs result in a cellular response through the activatio...
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| Main Authors: | , , , , , , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2012
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3303121/ https://ncbi.nlm.nih.gov/pubmed/22286059 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10750 |
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