Proteoliposome-based Selection of a Recombinant Antibody Fragment Against the Human M2 Muscarinic Acetylcholine Receptor

The development of antibodies against human G-protein-coupled receptors (GPCRs) has achieved limited success, which has mainly been attributed to their low stability in a detergent-solubilized state. We herein describe a method that can generally be applied to the selection of phage display librarie...

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Detalhes bibliográficos
Publicado no:Monoclon Antib Immunodiagn Immunother
Main Authors: Suharni, Nomura, Yayoi, Arakawa, Takatoshi, Hino, Tomoya, Abe, Hitomi, Nakada-Nakura, Yoshiko, Sato, Yumi, Iwanari, Hiroko, Shiroishi, Mitsunori, Asada, Hidetsugu, Shimamura, Tatsuro, Murata, Takeshi, Kobayashi, Takuya, Hamakubo, Takao, Iwata, So, Nomura, Norimichi
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2014
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4278166/
https://ncbi.nlm.nih.gov/pubmed/25545206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/mab.2014.0041
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