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Glycolytic inhibition causes spontaneous ventricular fibrillation in aged hearts

Selective glycolytic inhibition (GI) promotes electromechanical alternans and triggered beats in isolated cardiac myocytes. We sought to determine whether GI promotes triggered activity by early afterdepolarization (EAD) or delayed afterdepolarizations in intact hearts isolated from adult and aged r...

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Bibliographische Detailangaben
Hauptverfasser: Morita, Norishige, Lee, Jong-Hwan, Bapat, Aneesh, Fishbein, Michael C., Mandel, William J., Chen, Peng-Sheng, Weiss, James N., Karagueuzian, Hrayr S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302192/
https://ncbi.nlm.nih.gov/pubmed/21478408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00128.2011
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