Glycolytic inhibition causes spontaneous ventricular fibrillation in aged hearts

Selective glycolytic inhibition (GI) promotes electromechanical alternans and triggered beats in isolated cardiac myocytes. We sought to determine whether GI promotes triggered activity by early afterdepolarization (EAD) or delayed afterdepolarizations in intact hearts isolated from adult and aged r...

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Hlavní autoři: Morita, Norishige, Lee, Jong-Hwan, Bapat, Aneesh, Fishbein, Michael C., Mandel, William J., Chen, Peng-Sheng, Weiss, James N., Karagueuzian, Hrayr S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2011
Témata:
Cardiac Excitation and Contraction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302192/
https://ncbi.nlm.nih.gov/pubmed/21478408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00128.2011
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