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Suppression of Re-Entrant and Multifocal Ventricular Fibrillation by the Late Sodium Current Blocker Ranolazine

OBJECTIVES: The purpose of this study was to test the hypothesis that the late Na current blocker ranolazine suppresses re-entrant and multifocal ventricular fibrillation (VF). BACKGROUND: VF can be caused by either re-entrant or focal mechanism. METHODS: Simultaneous voltage and intracellular Ca(+2...

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Detalhes bibliográficos
Publicado no:J Am Coll Cardiol
Main Authors: Morita, Norishige, Lee, Jong Hwan, Xie, Yuanfang, Sovari, Ali, Qu, Zhilin, Weiss, James N., Karagueuzian, Hrayr S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4344130/
https://ncbi.nlm.nih.gov/pubmed/21232675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2010.07.045
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