Glycolytic inhibition causes spontaneous ventricular fibrillation in aged hearts

Selective glycolytic inhibition (GI) promotes electromechanical alternans and triggered beats in isolated cardiac myocytes. We sought to determine whether GI promotes triggered activity by early afterdepolarization (EAD) or delayed afterdepolarizations in intact hearts isolated from adult and aged r...

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Bibliografiske detaljer
Main Authors: Morita, Norishige, Lee, Jong-Hwan, Bapat, Aneesh, Fishbein, Michael C., Mandel, William J., Chen, Peng-Sheng, Weiss, James N., Karagueuzian, Hrayr S.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2011
Fag:
Cardiac Excitation and Contraction
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302192/
https://ncbi.nlm.nih.gov/pubmed/21478408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00128.2011
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