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Hepatocyte Growth Factor (HGF)/c-Met Signaling is required for Stem Cell Mediated Liver Regeneration
HGF/c-Met supports a pleiotrophic signal transduction pathway that controls stem cell homeostasis. Here, we directly addressed the role of c-Met in stem cell-mediated liver regeneration by utilizing mice harboring c-met floxed alleles and Alb-Cre or Mx1-Cre transgenes. To activate oval cells, the he...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3299882/ https://ncbi.nlm.nih.gov/pubmed/22095660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.24796 |
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