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Hepatocyte growth factor/c-met signaling pathway is required for efficient liver regeneration and repair

Hepatocyte growth factor/scatter factor c-met signaling pathway is of central importance during development as well as in tumorigenesis. Because homozygous null mice for either hgf/sf or c-met die in utero, we used Cre/loxP-mediated gene targeting to investigate the function of c-met specifically in...

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Bibliografiske detaljer
Main Authors: Huh, Chang-Goo, Factor, Valentina M., Sánchez, Aránzazu, Uchida, Koichi, Conner, Elizabeth A., Thorgeirsson, Snorri S.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC384772/
https://ncbi.nlm.nih.gov/pubmed/15070743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0306068101
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