Complex Drug Interactions of the HIV Protease Inhibitors 3: Effect of Simultaneous or Staggered Dosing of Digoxin and Ritonavir, Nelfinavir, Rifampin, or Bupropion

As part of a larger clinical drug-drug interaction (DDI) study aimed at in vitro to in vivo prediction of HIV protease inhibitor metabolic and transporter-based DDIs, we measured the inductive (staggered administration) and inductive plus inhibitory (simultaneously administered) effect of multiple d...

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Main Authors: Kirby, Brian J., Collier, Ann C., Kharasch, Evan D., Whittington, Dale, Thummel, Kenneth E., Unadkat, Jashvant D.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2012
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3286266/
https://ncbi.nlm.nih.gov/pubmed/22190694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.111.042705
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