Complex Drug Interactions of HIV Protease Inhibitors 2: In Vivo Induction and In Vitro to In Vivo Correlation of Induction of Cytochrome P450 1A2, 2B6, and 2C9 by Ritonavir or Nelfinavir

Drug-drug interactions (DDIs) with the HIV protease inhibitors (PIs) are complex, paradoxical (e.g., ritonavir/alprazolam), and involve multiple mechanisms. As part of a larger study to better understand these DDIs and to devise a framework for in vitro to in vivo prediction of these DDIs, we determ...

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Detaylı Bibliyografya
Asıl Yazarlar: Kirby, Brian J., Collier, Ann C., Kharasch, Evan D., Dixit, Vaishali, Desai, Pankaj, Whittington, Dale, Thummel, Kenneth E., Unadkat, Jashvant D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The American Society for Pharmacology and Experimental Therapeutics 2011
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Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226381/
https://ncbi.nlm.nih.gov/pubmed/21930825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.111.038646
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